Breast Cancer Connect
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Stay on Track: a Pilot Randomized Control Trial on the Feasibility of a Diet and Exercise Intervention in Patients With Breast Cancer Receiving Radiation Therapy

Stay on Track: a Pilot Randomized Control Trial on the Feasibility of a Diet and Exercise Intervention in Patients With Breast Cancer Receiving Radiation Therapy

Source : https://pubmed.ncbi.nlm.nih.gov/38530195/

Targeted lifestyle interventions during RT are feasible and could decrease cardiovascular comorbidities in patients with breast cancer. Larger-scale implementation with longer follow-up can better determine interventions that influence cardiometabolic health...

Targeted lifestyle interventions during radiotherapy are feasible and could decrease cardiovascular comorbidities in patients with breast cancer.

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The 10-year risk of developing a second primary breast cancer was ≈2% among women who did not carry a germline pathogenic variant compared with ≈9% among women who carried such a variant.

  • 2yr
    obviously testing for BRCA is important; what to do if negative is still not clear
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Omitting Axillary Dissection in Breast Cancer with Sentinel-Node Metastases

Omitting Axillary Dissection in Breast Cancer with Sentinel-Node Metastases

Source : https://pubmed.ncbi.nlm.nih.gov/38598571/

The omission of completion axillary-lymph-node dissection was noninferior to the more extensive surgery in patients with clinically node-negative breast cancer who had sentinel-node macrometastases, most of whom received nodal radiation...

The estimated 5-year recurrence-free survival were 89.7% in the sentinel-node biopsy-only and 88.7% in the dissection groups, with a country-adjusted HR for recurrence or death of 0.89.

  • 2yr
    it is obviously important to take in consideration pretreatment number of LN and the overall risk of disease
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The 2-year disease-free and OS rates were 94.0% and 99.8%, respectively.

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Clinical, Epidemiologic, and Pathologic Significance of ERBB2-Low Expression in Breast Cancer

Clinical, Epidemiologic, and Pathologic Significance of ERBB2-Low Expression in Breast Cancer

Source : https://pubmed.ncbi.nlm.nih.gov/38517439/

These findings suggest that there were clinical, pathological, and epidemiological differences between ERBB2-low and ERBB2-negative BC, raising the possibility that ERBB2-low might be a unique biologic entity.

These findings suggest that there were clinical, pathological, and epidemiological differences between ERBB2-low and ERBB2-negative breast cancer, raising the possibility that ERBB2-low might be a unique biologic entity.