There was no benefit of aspirin 300 mg/day on breast cancer recurrence and survival rates.
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Albert Dekker1yrTrue but it will definitely increase involvement in ones own care and decision to make other healthy choices
Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2– and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study
Source : https://pubmed.ncbi.nlm.nih.gov/38652877/
In patients with heavily pretreated advanced HR+/HER2- BC and TNBC, Dato-DXd demonstrated promising clinical activity and a manageable safety profile. Dato-DXd is currently being evaluated in phase III studies.
Median PFS rates in patients with hormone receptor positive/human epidermal growth factor receptor 2 negative breast cancer and triple-negative breast cancer were 8.3 and 4.4 months, respectively.
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Albert Dekker1yrI think that is applicable to all ADC; question which one offers best benefit to risk ratio
The overall frequency of pathogenic or likely pathogenic CDH1 variants was 1.5% and was associated with age ≤45 years at lobular breast cancer diagnosis and positive family history of breast cancer.
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Albert Dekker1yrI think the more we learn the more mild variants and the incomplete penetrance we will find
Stay on Track: a Pilot Randomized Control Trial on the Feasibility of a Diet and Exercise Intervention in Patients With Breast Cancer Receiving Radiation Therapy
Source : https://pubmed.ncbi.nlm.nih.gov/38530195/
Targeted lifestyle interventions during RT are feasible and could decrease cardiovascular comorbidities in patients with breast cancer. Larger-scale implementation with longer follow-up can better determine interventions that influence cardiometabolic health...
Targeted lifestyle interventions during radiotherapy are feasible and could decrease cardiovascular comorbidities in patients with breast cancer.
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Albert Dekker1yrhard to do during but critical afterwards
The 10-year risk of developing a second primary breast cancer was ≈2% among women who did not carry a germline pathogenic variant compared with ≈9% among women who carried such a variant.
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Albert Dekker1yrobviously testing for BRCA is important; what to do if negative is still not clear