Study Protocol of SURVIVE HERoes (NCT06643585): Trastuzumab Deruxtecan for molecular relapse in HER2+/ Low early breast cancer with ctDNA positivity after primary therapy - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41259337/
Treating ctDNA positive patients without radiographic signs of recurrence is a novel approach. If SURVIVE HERoes and similar studies targeting MRD will be positive, this may lead the way to...
SURVIVE HERoes is a phase III trial testing trastuzumab deruxtecan versus standard care in HER2+/low early breast cancer with ctDNA-positive molecular relapse, aiming to improve ctDNA clearance and advance MRD-guided therapy.
Diagnosis of Ectopic Intrathyroidal Parathyroid Adenoma with Nodular Goiter by 18F Fluorocholine: A Case Report - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35603434/
The occurrence of ectopic intrathyroidal parathyroid adenoma (EPTA) is very rare, which causes some difficulties in diagnosis and complicates treatment. In addition, the occurrence of EPTA with nodular goiter (NG)...
Ectopic intrathyroidal parathyroid adenoma with nodular goiter is rare and challenging to diagnose; this case highlights the value of fluorocholine imaging and cytology for accurate identification and management.
Cancer survivorship programs for patients from culturally and linguistically diverse (CALD) backgrounds: a scoping review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37572196/
Ensuring culturally sensitive and specific delivery of cancer survivorship programs and interventions is paramount in providing optimal care for survivors from CALD backgrounds.
This review of 26 studies on cancer survivorship programs for culturally and linguistically diverse populations found most U.S.-based, focusing on breast cancer; multimodal, bilingual, community-informed interventions improved quality of life, highlighting cultural sensitivity’s importance despite barriers.
Ravulizumab Can Effectively Treat Ischemic Enteritis Caused by Paroxysmal Nocturnal Hemoglobinuria - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37558427/
Ischemic colitis is a common disease with a good prognosis; however, complications can occur in the presence of a serious underlying disease. Herein, we present a case report in which...
An 82-year-old woman with ischemic colitis secondary to paroxysmal nocturnal hemoglobinuria achieved remission and reduced transfusion dependence following ravulizumab therapy, underscoring complement inhibition’s efficacy in managing thrombotic PNH-related intestinal ischemia.
Nasopharyngeal Metastasis from Breast Carcinoma: A Case Report and a Review of the Literature - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35943955/
Metastasis to the nasopharynx is a rare clinical entity. Breast carcinoma is one of the primary tumors that can be responsible for a nasopharyngeal metastasis, which is an extremely rare...
A rare case of nasopharyngeal metastasis from breast carcinoma presenting with hearing loss and tinnitus; biopsy confirmed ER/PR-positive adenocarcinoma, and chemotherapy achieved partial regression, highlighting diagnostic challenges in secondary nasopharyngeal tumors.