Breast Cancer Connect
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Characterization of Frequently Mutated Cancer Genes and Tumor Mutation Burden in Chinese Breast Cancer - PubMed

Characterization of Frequently Mutated Cancer Genes and Tumor Mutation Burden in Chinese Breast Cancer - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33968723/

doi: 10.3389/fonc.2021.618767. 1 Department of Breast Cancer, Cancer Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. 2 Department of Breast, Foshan Women and Children Hospital, Foshan,...

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Advances in Therapy for Hormone Receptor (HR)-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Advanced Breast Cancer Patients Who Have Experienced Progression After Treatment with CDK4/6 Inhibitors - PubMed

Advances in Therapy for Hormone Receptor (HR)-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Advanced Breast Cancer Patients Who Have Experienced Progression After Treatment with CDK4/6 Inhibitors - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33976551/

Approximately 70% of breast cancer (BC) cases are hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-) BC. Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors have acted as...

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pT3N0M0 Breast Cancer with Postmastectomy Radiotherapy | CMAR

pT3N0M0 Breast Cancer with Postmastectomy Radiotherapy | CMAR

Source : https://www.dovepress.com/outcomes-in-patients-with-pt3n0m0-breast-cancer-with-and-without-postm-peer-reviewed-fulltext-article-CMAR

It is confusing for both doctors and node-negative non-metastatic breast cancer patients with tumors of 5 cm or larger to decide whether to receive post-operation radiotherapy. Therefore, we did this...

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Key Points
• In the current study, researchers retrospectively assessed the clinical outcomes of 45 breast cancer patients receiving stereotactic radiosurgery (SRS) for 72 brain metastases.
• The median number of brain metastases treated was 2, with a range of 1 to 20. The median OS dating from BM diagnosis was 27.6 months and that from...

Stereotactic radiosurgery for patients with breast cancer brain oligometastases - molecular subtypes and clinical outcomes - PubMed

Stereotactic radiosurgery for patients with breast cancer brain oligometastases - molecular subtypes and clinical outcomes - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33948296/

2021 Feb 25;26(1):1-11. doi: 10.5603/RPOR.a2021.0001. 1 Division of Radiation Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia. Free PMC article Ivica Ratosa et al. Rep Pract Oncol Radiother. Free PMC article...

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Studying Tumor Angiogenesis and Cancer Invasion in a Three-Dimensional Vascularized Breast Cancer Micro-Environment - PubMed

Studying Tumor Angiogenesis and Cancer Invasion in a Three-Dimensional Vascularized Breast Cancer Micro-Environment - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33857356/

Metastatic breast cancer is one of the deadliest forms of malignancy, primarily driven by its characteristic micro-environment comprising cancer cells interacting with stromal components. These interactions induce genetic and metabolic...