Breast Cancer Connect
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First- and second-line treatment strategies for hormone-receptor (HR)-positive HER2-negative metastatic breast cancer: A real-world study - PubMed

First- and second-line treatment strategies for hormone-receptor (HR)-positive HER2-negative metastatic breast cancer: A real-world study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33812267/

Our real-world data demonstrated that ET-CDKi represents the best option for 1 st L luminal-MBC compared to ET and CT. Also, the present study pointed out that 2 nd L...

  • 5yr
    Key Points • In the current study published in Breast, Italian researchers compared endocrine therapy (ET) plus cyclin-dependent-kinases 4/6 inhibitors (CDK4/6i) for the treatment of 717 patients with luminal-metastatic breast cancer Show More
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MicroRNA-206 suppresses mesothelioma progression via the Ras signaling axis - PubMed

MicroRNA-206 suppresses mesothelioma progression via the Ras signaling axis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33996251/

doi: 10.1016/j.omtn.2021.04.001. 1 Thoracic Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. 2 Urology Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD,...

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ESMO 2020: highlights in breast cancer

ESMO 2020: highlights in breast cancer

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090520/

Despite the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, results of several pertinent studies in the field of breast cancer (BC) were presented in a virtual format at...

  • 5yr
    Key Points • This article sums up the findings from several key trials presented at ESMO 2020. Here’s a look at two similar trials with contradicting results: MonarchE and the PALLAS Show More
  • 5yr
    Key Points • This article sums up the findings from several key trials presented at ESMO 2020. Here’s a look at two similar trials with contradicting results: MonarchE and the PALLAS trial. • In Show More
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44-Year-Old Female with Locally Advanced Breast Cancer

Nancy, a 44-year-old woman of five, was referred for treatment of locally advanced breast cancer. She had a massive tumor with skin thickening in her right breast. Ultrasound was used instead of mammography due to the hardness of her right breast — revealing pronounced skin thickening, an...

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UChicago study finds lasofoxifene a promising treatment for resistant breast cancer

UChicago study finds lasofoxifene a promising treatment for resistant breast cancer

Source : https://www.eurekalert.org/pub_releases/2021-05/uocm-usf051321.php

In a study carried out in mice at the University of Chicago, researchers found that lasofoxifene outperformed fulvestrant, the current gold-standard drug, in reducing or preventing primary tumor growth. It...