Abemaciclib as initial therapy for advanced breast cancer: MONARCH 3 updated results in prognostic subgroups - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34158513/
In MONARCH 3, continuous dosing of abemaciclib with an aromatase inhibitor (AI) conferred significant clinical benefit to postmenopausal women with HR+, HER2- advanced breast cancer. We report data for clinically...
Adjuvant Chemotherapy for Low-Clinical-Risk Breast Cancer Defined by Modified Version of Adjuvant! Online: A Propensity Score Matched SEER Analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34012370/
This retrospective study provides evidence that CT may not be beneficial to patients 50 years of age or older with HR-positive, HER2-negative, axillary node-negative breast cancer and additionally defined as...
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Naveed Saleh, MD, MS – Skipta Team5yrKey Points • In the current study, researchers retrospectively assessed whether 56 patients with EGFR-mutated lung cancer were effectively be treated with PD-1/PD-L1 therapy plus chemotherapy with or without bevacizumab. These Show More
Prediction of Pretreatment 18F-FDG-PET/CT Parameters on the Outcome of First-Line Therapy in Patients with Metastatic Breast Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34007206/
1 Department of Medical Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China. 2 Department of Nuclear Medicine, Fudan University...
Alpelisib-Induced Diabetic Ketoacidosis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34084688/
We present the third case of alpelisib-induced diabetic ketoacidosis. Alpelisib is an antineoplastic agent that inhibits phosphatidylinositol 3-kinase (PI3K), which plays a key role in multiple biological processes such as...
Epithelial-Mesenchymal-Transition-Like Circulating Tumor Cell-Associated White Blood Cell Clusters as a Prognostic Biomarker in HR-Positive/HER2-Negative Metastatic Breast Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34150608/
Our data provide evidence that the emergence of CTC-WBC clusters underwent EMT before treatment is associated with significantly poorer PFS in HR-positive/HER2-negative metastatic breast cancer patients receiving docetaxel plus capecitabine,...