Optimizing treatment selection, and sequencing decisions for Management of HR-Positive, HER2-Negative advanced breast cancer - Proceedings from breast cancer expert group meeting - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34372853/
The current article will serve as a comprehensive guide for optimizing the management of HR + HER2 - mBC. The proposed breast cancer registry will help identify unmet needs and...
Abemaciclib plus fulvestrant in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in premenopausal women: subgroup analysis from the MONARCH 2 trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34425869/
doi: 10.1186/s13058-021-01463-2. 1 Department of Oncology, University Hospitals Leuven, KU Leuven-University of Leuven, Herestraat 49, 3000, Leuven, Belgium. [email protected]. 2 Department of Medicine (Hematology/Oncology), University of California San Francisco Helen...
Combination of ZEN-3694 with CDK4/6 inhibitors reverses acquired resistance to CDK4/6 inhibitors in ER-positive breast cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34385584/
doi: 10.1038/s41417-021-00375-9. Online ahead of print. 1 Zenith Epigenetics, Suite 300, 4820 Richard Road SW, Calgary, AB, T3E 6L1, Canada. [email protected]. 2 Zenith Epigenetics, Suite 300, 4820 Richard Road SW,...
Establishment of Prognostic Nomograms for Predicting the Survival of HR-Positive, HER2-Negative Metastatic Breast Cancer Patients Treated with Everolimus - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34408400/
We constructed convenient nomogram models for patients with HR+, HER2- metastatic breast cancer to individually predict their potential benefits from everolimus in the metastatic setting. The models showed good performance...
Development of an arteriolar niche and self-renewal of breast cancer stem cells by lysophosphatidic acid/protein kinase D signaling - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34168243/
Breast cancer stem cells (BCSCs) are essential for cancer growth, metastasis and recurrence. The regulatory mechanisms of BCSC interactions with the vascular niche within the tumor microenvironment (TME) and their...