Breast Cancer Connect
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Association of Breast Tumour Expression of Cannabinoid Receptors CBR1 and CBR2 with Prognostic Factors and Survival in Breast Cancer Patients - PubMed

Association of Breast Tumour Expression of Cannabinoid Receptors CBR1 and CBR2 with Prognostic Factors and Survival in Breast Cancer Patients - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34575629/

Cannabinoid receptors (CBR) are potential therapeutic targets for breast cancer. However, the role of CBR in breast cancer survival remains poorly understood. Data from a prospective cohort of 522 women...

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    Key Points • Source: Journal of Personalized Medicine • Conclusion/Relevance: “This is the first study to evaluate both CBR1 [cannabinoid receptor 1] and CBR2 [cannabinoid receptor 2] expression in association with breast Show More
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Real-world benefit of combination palbociclib and endocrine therapy for metastatic breast cancer and correlation with neutropenia - PubMed

Real-world benefit of combination palbociclib and endocrine therapy for metastatic breast cancer and correlation with neutropenia - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34590788/

The effectiveness of palbociclib and endocrine therapy in the treatment of HR-positive, HER2-negative mBC in the real-world setting is similar to the efficacy reported in the PALOMA-2 trial. Patients with...

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Myocardial dysfunction caused by abemaciclib: a case report - PubMed

Myocardial dysfunction caused by abemaciclib: a case report - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34567946/

A 68-year-old female patient with metastatic breast cancer presented 12 weeks after starting chemotherapy with abemaciclib and fulvestrant with breathlessness, peripheral edema, and weight gain. Brain natriuretic peptide (BNP) and...

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Molecular Prognostic Factors for Distant Metastases in Premenopausal Patients with HR+/HER2- Early Breast Cancer - PubMed

Molecular Prognostic Factors for Distant Metastases in Premenopausal Patients with HR+/HER2- Early Breast Cancer - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34575612/

Molecular factors that drive metastasis in premenopausal patients with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-), early breast cancer (EBC) are largely unknown. To identify...

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Combined everolimus and endocrine therapy in advanced HR-positive, HER2-negative Chinese breast cancer patients: a retrospective study - PubMed

Combined everolimus and endocrine therapy in advanced HR-positive, HER2-negative Chinese breast cancer patients: a retrospective study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34532471/

EVE combined with endocrine therapy is an effective treatment option for Chinese patients with hormone-receptor-positive (HR+), human epidermal growth factor receptor-2-negative (HER2-) breast cancer, although EVE + FUL was not...



Conclusions: EVE combined with endocrine therapy is an effective treatment option for Chinese patients with hormone-receptor-positive (HR ), human epidermal growth factor receptor-2-negative (HER2-) breast cancer, although EVE FUL was not superior to EVE AI. Liver metastasis and brain metastasis were independent risk factors for successful...