Effects of Primary Tumor Resection on Metastatic Breast Cancer Survival and the Predictive Power of Neutrophil: Lymphocyte Ratio on Prognosis
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496121/
Keywords: Metastatic breast cancer, primary tumor resection, neutrophil-to-lymphocyte ratio, survival Key Points * DSS was 43.5 months in the PTR group and 30.7 months in the ST group. Survival difference...
Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34529000/
doi: 10.1001/jamaoncol.2021.3690. Online ahead of print. 1 Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston. 2 Department of Surgery, University of California, San Francisco. 3 Department...
Use of classifiers to optimise the identification and characterisation of metastatic breast cancer in a nationwide administrative registry - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34549678/
doi: 10.1080/0284186X.2021.1979645. Online ahead of print. 1 Department of Oncology, Faculty of Medicine and Health, Örebro University Hospital, Örebro, Sweden. 2 Nordic Market Access AB, Stockholm, Sweden. 3 Parexel International,...
Developing a biomechanical model-based elasticity imaging method for assessing hormone receptor positive breast cancer treatment-related myocardial stiffness changes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34604442/
Purpose: Assessing cardiotoxicity as a result of breast cancer therapeutics is increasingly important as breast cancer diagnoses are trending younger and overall survival is increasing. With evidence showing that prevention...
Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34611473/
The major adaptive response to hypoxia involves hypoxia-inducible factor HIF-1α which is regulated by von Hippel Lindau (VHL) E3 ligase. We previously observed a stabilization of HIF-1α by cyclin-dependent kinases...