CDK4/6 Inhibition and Radiation as a Treatment Strategy to Improve Local Disease Control in Breast Cancers With Poor Prognoses - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34700581/
RB loss mitigates CDK4/6 inhibitor-mediated radiosensitization of both ER+ and TNBC cells. Loss of RB expression prevents CDK4/6i-mediated radiosensitization, suggesting that RB expression may be a valuable clinical biomarker to...
Peritoneal Metastasis After Treated With Abemaciclib Plus Fulvestrant for Metastatic Invasive Lobular Breast Cancer: A Case Report and Review of the Literature - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34690920/
Peritoneal metastases from invasive lobular carcinoma (ILC) of breast are uncommon and usually related to poor prognosis due to difficulty of detection in clinical practice and drug resistance. Therefore, recognizing...
Niraparib for Advanced Breast Cancer with Germline BRCA1 and BRCA2 Mutations: the EORTC 1307-BCG/BIG5-13/TESARO PR-30-50-10-C BRAVO Study
Source : https://clincancerres.aacrjournals.org/content/27/20/5482
Purpose: To investigate the activity of niraparib in patients with germline-mutated BRCA1/2 (g BRCA m) advanced breast cancer. Patients and Methods: BRAVO was a randomized, open-label phase III trial.
Japanese subgroup analysis of the phase 3 MONARCH 3 study of abemaciclib as initial therapy for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34661821/
doi: 10.1007/s12282-021-01295-0. Online ahead of print. 1 National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan. 2 National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan. 3 Eli Lilly Japan K.K., Kobe,...
Prognostic value of tumor-infiltrating lymphocytes in estrogen receptor-positive and human epidermal growth factor receptor 2-negative breast cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34671471/
doi: 10.3892/mco.2021.2414. 1 Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan. 2 Division of Breast and Endocrine Surgery, Gunma University Hospital, Maebashi, Gunma...