The role of ferroptosis-related genes for overall survival prediction in breast cancer - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34741349/

doi: 10.1002/jcla.24094. Online ahead of print. 1 Department of Thyroid and breast surgery, The Second Affiliated Hospital of Soochow University, Suzhou, China. 2 Department of Thyroid and breast surgery, Traditional...

Obesity and Breast Cancer Risk in Men: A National Case-Control Study in England and Wales - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34738071/

Obesity at all adult ages, particularly recent abdominal obesity, is associated with raised risk of breast cancer in men, probably because of the conversion of testosterone to estrogen by aromatase...

Correlation between molecular prognostic factors and magnetic resonance imaging intravoxel incoherent motion histogram parameters in breast cancer - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34740800/

The ADC 10th percentile had the largest area under the curve in the ER-negative ROC analysis, and the ADC standard deviation was the most valuable in the correlation analysis of...

Skin Toxicities with Cyclin-Dependent Kinase 4/6 Inhibitors in Breast Cancer: Signals from Disproportionality Analysis of the FDA Adverse Event Reporting System - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34699032/

doi: 10.1007/s40257-021-00645-0. Online ahead of print. 1 Pharmacology Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum-University of Bologna, Via Irnerio 48, 40126, Bologna, Italy. [email protected]. 2 Pharmacology Unit,...

ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34700018/

Abemaciclib is the third cyclin-dependent kinase (CDK) 4/6 inhibitor approved for the treatment of breast cancer and currently under investigation for other malignancies, including brain cancer. Primarily CYP3A4 metabolizes abemaciclib,...