Skip to main content
  • Saved

Commented on 's Post

The application of new gastric cancer screening score system for gastric cancer screening and risk assessment of gastric precancerous lesions in China - PubMed

The application of new gastric cancer screening score system for gastric cancer screening and risk assessment of gastric precancerous lesions in China - PubMed

Source :

https://pubmed.ncbi.nlm.nih.gov/35868004/

Objective: To evaluate the value of new gastric cancer screening score system for risk assessment of gastric precancerous lesions. Methods: A total of 520 patients were enrolled after the examination of endoscopy at Endoscopy Center, Department of Gastroenterology, from June 2018 to Dec ...

  • July 25, 2022
    Key Points
    • Source: Scandinavian Journal of Gastroenterology
    • Conclusion: “The new gastric cancer screening score system is closely linked with histological OLGA/OLGIM staging system in the risk assessment of gastric precancerous lesions. The role of new gastric cancer screening score system in future gastric precancerous lesions screening and high-risk population identifying was promising.”
    • Chinese researchers divided 520 patients into 3 groups (i.e., low risk, middle risk, high risk) based on gender, age, serum helicobacter pylori antibody test, pepsinogen I (PGI), pepsinogen II (PGII), pepsinogen I/II ratio (PGR), and gastrin-17 test results before endoscopy. They then followed for the development of gastric cancer on endoscopy.
    • Per the range and degree of atrophy/intestinal metaplasia, the researchers divided participants into 5 groups characterized by OLGA/OLGIM staging system. They compared the levels of PG I, PG II, and PGR among the different groups. They then looked for relationships between the novel scores on the gastric cancer screening system and OLGA/OLGIM staging system.
    • They found that the PGR levels were inversely associated with OLGIM stages, and the PGI and PGR levels were inversely associated with OLGA stages. The high-risk group (i.e., Group C) exhibited detection rates of gastric cancer/atrophic gastritis. On further analysis, OLGA/OLGIM and the new gastric cancer screening score system are significantly correlated (P < .001).