The rate of prostatic involvement in men treated with radical cystectomy for muscle invasive bladder cancer
Source : https://www.practicalradonc.org/article/S1879-8500(22)00193-X/fulltext
Radical cystoprostatectomy (RC) is one standard treatment for muscle-invasive bladder cancer (MIBC) in male patients. Another therapeutic option is trimodal therapy (TMT). Including the prostate in the TMT radiotherapy volume is based on MIBC surgical series showing prostatic stromal (PS) involvement.
Conclusion: The high rate of pathological PS involvement seen in cT2 patients and the lack of ability of cT stage to predict PS involvement supports routinely treating the prostate in TMT. Patients with pre-operatively identified bladder neck/trigone tumors, urethral involvement, positive lymph nodes, or prostatic involvement are a subset at even higher risk of having pathologic PS involvement.