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RET Inhibitors in Non-Small-Cell Lung Cancer - PubMed

RET Inhibitors in Non-Small-Cell Lung Cancer - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34503226/

RET rearrangements are observed in 1-2% of non-small-cell lung cancer (NSCLC) patients and result in the constitutive activation of downstream pathways normally implied in cell proliferation, growth, differentiation and survival. In NSCLC patients, RET rearrangements have been associated with a hist ...