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Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers - PubMed

Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers - PubMed

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https://pubmed.ncbi.nlm.nih.gov/34310819/

ALK, ROS1, and RET kinase fusions are important predictive biomarkers of tyrosine kinase inhibitors (TKIs) in non-small-cell lung cancer (NSCLC). Analysis of cell-free DNA (cfDNA) provides a noninvasive method to identify gene changes in tumor cells. The present study sought to use cfRNA and cfDNA f ...