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October 09, 2022
Predictive value of baseline metabolic tumor volume for non-small-cell lung cancer patients treated with immune checkpoint inhibitors: A meta-analysis

Predictive value of baseline metabolic tumor volume for non-small-cell lung cancer patients treated with immune checkpoint inhibitors: A meta-analysis

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487526/

Ke Zhu, 1 , 2 Danqian Su, 1 , 2 Jianing Wang, 1 , 2 Zhouen Cheng, 1 , 2 Yiqiao Chin, 1 , 2 Luyin Chen, 1 , 2 Chingtin Chan, 1 , 2 Rongcai Zhang, 1 , 2 Tianyu Gao, 1 Xiaosong Ben, 3 , * and Chunxia Jing 1 , 4 , * Immune checkpoint inhibitors (ICIs) have emerged as a promising treatment option for advanced non-small-cell lung cancer (NSCLC) patients, highlighting the need for biomarkers to identify responders and predict the outcome of ICIs.


Conclusions: High level of baseline MTV corresponded to shorter PFS and OS, especially when the cut-off value was set between 50-100 cm3. MTV is a potential predictive value for the outcome of ICIs in NSCLC patients.

  • October 09, 2022
    makes sense to some degree. It was well known with traditional chemotherapy.