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Gene expression analysis of MCF7 cell lines of breast cancer treated with herbal extract of Cissampelos pareira revealed association with viral diseases - PubMed

The study identified 418 differentially expressed genes (DEGs) using bioinformatics tools. The gene ontology of pathway enrichments employed by GO and KEGG enrichment analyses of down-regulated and up-regulated DEGs were ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33907720/

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  • 1 day 2 hours
    Key Points • Investigators identified 418 differentially expressed genes (DEGs) in breast cancer cell lines using bioinformatics tools. They found in silico evidence for candidate genes integral for the inhibition, adhesion, Show More
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Determinants of Delayed Presentation and Advanced-Stage Diagnosis of Breast Cancer in Africa: A Systematic Review and Meta-Analysis - PubMed

1 Department of Surgery, University of Ilorin and University of Ilorin Teaching Hospital, Ilorin, Kwara State. Nigeria. 2 Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Kwara state. Nigeria. ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33906291/

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The use of adjuvant radiation therapy in male breast cancer and its impact on outcomes - PubMed

doi: 10.1016/j.ctarc.2021.100359. Online ahead of print. 1 Allegheny Health Network, Department of Internal Medicine, 320 E. North Avenue, Pittsburgh, PA 15212, United States. 2 Allegheny Health Network Cancer Institute, Division ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33812181/

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Japanese subpopulation analysis of MONARCH 2: phase 3 study of abemaciclib plus fulvestrant for treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer that progressed on endocrine therapy - PubMed

doi: 10.1007/s12282-021-01239-8. Online ahead of print. 1 Saitama Cancer Center, Saitama, Japan. 2 National Hospital Organization, Osaka National Hospital, Osaka, Japan. 3 Department of Breast Oncology, Aichi Cancer Center Hospital, ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33797023/

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Financial constraints on genetic counseling and further risk-management decisions among U.S. women at elevated breast cancer risk - PubMed

Clinical guidelines recommend that women at high risk of breast cancer should consider various risk-management options, which remain widely underutilized. We conducted semi-structured, qualitative interviews with 50 high-risk women to ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33749063/

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The bone microenvironment increases phenotypic plasticity of ER + breast cancer cells - PubMed

Estrogen receptor-positive (ER + ) breast cancer exhibits a strong bone tropism in metastasis. How the bone microenvironment (BME) impacts ER signaling and endocrine therapy remains poorly understood. Here, we ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33878299/

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    Key Points • Estrogen receptor-positive (ER+) breast cancer has a propensity to metastasize to bone, however the means by which the bone microenvironment (BME) affects ER signaling and endocrine therapy needs to Show More
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New study reveal targeted therapy working in early breast cancer

Targeted therapy in early stages of breast cancer can pave the way for a notable higher success rate, shows a study from the University of Bergen, Norway (UiB). PARP (Poly ..... see more

Source : https://www.eurekalert.org/pub_releases/2021-04/tuob-nsr042021.php

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Trastuzumab deruxtecan for treating HER2-positive unresectable or metastatic breast cancer after 2 or more anti-HER2 therapies [ID2697]

The Appraisal Committee has prepared a Final Appraisal Document (FAD) on trastuzumab deruxtecan for treating HER2-positive unresectable or metastatic breast cancer after 2 or more anti-HER2 therapies and submitted it ..... see more

Source : https://www.nice.org.uk/guidance/gid-ta10582/documents/html-content-2

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Patent awarded for ULM professor's research into olive oil treatment for breast cancer

The University of Louisiana Monroe has announced a U.S. Patent has been awarded based on research led by a ULM College of Pharmacy professor. Khalid El Sayed, Ph.D., a professor ..... see more

Source : https://www.thenewsstar.com/story/news/education/2021/04/20/ulm-prof-gets-patent-breast-cancer-research/7303900002/

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Treatment patterns for patients with advanced/metastatic cancers by site of care - PubMed

Objectives: To compare treatments, overall survival (OS), and total costs among patients receiving anticancer therapy in hospital outpatient vs physician office settings. Study design: This retrospective observational study utilized claims ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33877777/

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    Key Points • In this longitudinal study published in JAMA, researchers determined 5-year locoregional recurrence-free survival (LRFS) rate and disease-free survival (DFS) rate after sentinel lymph node biopsy (SLNB) and radiotherapy (RT) Show More
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Liquid Biopsy Augments MRI for Predicting Response to Neoadjuvant Treatment in Patients With Breast Cancer | AACR | News Releases

A liquid biopsy test to assess plasma cell-free DNA (cfDNA) integrity could improve the accuracy of magnetic resonance imaging (MRI) for predicting the achievement of complete response among patients with ..... see more

Source : https://www.aacr.org/about-the-aacr/newsroom/news-releases/liquid-biopsy-augments-mri-for-predicting-response-to-neoadjuvant-treatment-in-patients-with-breast-cancer/

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MSK Researchers Target Side Effects More Common in Black Women with Breast Cancer

The moment she was diagnosed with breast cancer at age 55, Brooklyn resident Debra E. Edwards felt a combination of fear and guilt. "I made a terrible mistake by putting ..... see more

Source : https://www.mskcc.org/news/msk-researchers-target-side-effects-more-common-black-women-breast

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Association of Obesity with Breast Cancer Outcome in Relation to Cancer Subtypes: A Meta-Analysis | Request PDF

Request PDF | Association of Obesity with Breast Cancer Outcome in Relation to Cancer Subtypes: A Meta-Analysis | Background: Obesity at breast cancer (BC) diagnosis has been associated with poor ..... see more

Source : https://www.researchgate.net/publication/349571028_Association_of_Obesity_with_Breast_Cancer_Outcome_in_Relation_to_Cancer_Subtypes_A_Meta-Analysis

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Greetings, Skipta Community:
We have summarized the following peer-reviewed journal article for your consideration. We welcome your feedback.

TITLE: Sentinel node biopsy should not be ..... see more

Sentinel Node Biopsy Should Not be Routine in Older Patients with ER-Positive HER2-Negative Breast Cancer Who Are Willing and Able to Take Hormone Therapy - PubMed

doi: 10.1245/s10434-021-09839-6. Online ahead of print. 1 Providence Breast Centre, Mount Saint Joseph Hospital, Vancouver, BC, Canada. EMcKevitt@providencehealth.bc.ca. 2 Department of Surgery, BC Cancer, Vancouver, Canada. EMcKevitt@providencehealth.bc.ca. 3 Department of ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33817760/

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61-Year-Old Woman of Jewish Heritage Diagnosed with Breast Cancer

A 61-year-old woman of Ashkenazi Jewish ancestry was referred for evaluation of a palatable mass that ..... see more

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  • 3 weeks 3 days
    Recommend surgical consultation for lumpectomy/sentinel node biopsy, then may need OncotypeDx to decide on adjuvant therapy. Would be advisable to get COVID vaccine but not mandatory
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De-escalation of radiation therapy in patients with stage I, node-negative, HER2-positive breast cancer - PubMed

In the modern era, highly effective anti-HER2 therapy is associated with low local-regional recurrence (LRR) rates for early-stage HER2+ breast cancer raising the question of whether local therapy de-escalation by ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33767168/

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[Full text] Association of ET and Dementia in Women with Breast Cancer | BCTT

Globally, breast cancer is the most common type of cancer diagnosed in women with over 270,000 new cases estimated in 2020 in the United States alone. However, despite this high ..... see more

Source : https://www.dovepress.com/association-of-endocrine-therapy-and-dementia-in-women-with-breast-can-peer-reviewed-fulltext-article-BCTT

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Sentinel Node Biopsy Should Not be Routine in Older Patients with ER-Positive HER2-Negative Breast Cancer Who Are Willing and Able to Take Hormone Therapy - PubMed

doi: 10.1245/s10434-021-09839-6. Online ahead of print. 1 Providence Breast Centre, Mount Saint Joseph Hospital, Vancouver, BC, Canada. EMcKevitt@providencehealth.bc.ca. 2 Department of Surgery, BC Cancer, Vancouver, Canada. EMcKevitt@providencehealth.bc.ca. 3 Department of ..... see more

Source : https://pubmed.ncbi.nlm.nih.gov/33817760/