A Rare Case of Concurrent Tropheryma Whipplei and Pneumocystis Jirovecii Pneumonia in a Patient During Endocrine Therapy for Breast Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41773230/
Tropheryma whipplei (TW), a rare Gram-positive bacterium, is an uncommon cause of pulmonary infection, typically being reported in the context of gastrointestinal or neurological Whipple's disease. We present a case...
Case report describes concurrent Tropheryma whipplei and Pneumocystis jirovecii pneumonia in a breast cancer patient receiving endocrine therapy, diagnosed via metagenomic sequencing and successfully treated with targeted antimicrobial therapy.
This meta-analysis of six RCTs (803 patients) shows neoadjuvant pertuzumab plus trastuzumab significantly improves pathological complete response, event-free survival, and disease-free survival versus trastuzumab alone, with manageable safety profiles in HER2-positive breast cancer.
Case Report: Primary cutaneous apocrine carcinoma mimicking breast carcinoma - a rare diagnostic challenge - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41704473/
This case underscores the importance of an interdisciplinary approach in diagnosing axillary neoplasms and illustrates the valuable role of a high-volume, multidisciplinary skin cancer center in optimizing patient management. Although...
Case of primary cutaneous apocrine carcinoma initially misdiagnosed as breast carcinoma due to overlapping features. Multidisciplinary evaluation enabled accurate diagnosis, complete excision, and radiotherapy, highlighting importance of broad differential and specialized care.
Hallmarks of cancer in canine mammary tumors: Insights into a potential model for human triple-negative breast cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41654097/
Human breast cancer (HBC) is a complex disease with several molecular subtypes, posing challenges in diagnosis and treatment. Among these subtypes, triple-negative breast cancer (TNBC) is particularly challenging due to...
Review compares cancer hallmarks in canine mammary carcinomas and human triple-negative breast cancer, highlighting biological parallels, model potential, and translational challenges, supporting comparative oncology and future personalized therapeutic research efforts.
Case Report: Comparison different response after neoadjuvant chemotherapy of the breast with cell-in-cell-report of two cases - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41641261/
Neoadjuvant chemotherapy (NACT) is commonly applied in human epidermal growth factor receptor 2 (HER2)-positive breast cancer to reduce tumor size and increase the likelihood of breast-conserving surgery. However, predictive markers...
Two HER2-positive breast cancer cases showed contrasting responses to neoadjuvant chemotherapy; changes in cell-in-cell structures correlated with treatment response, suggesting CIC dynamics may serve as potential predictive markers.