Pegfilgrastim Prophylaxis is Effective in the Prevention of Febrile Neutropenia and Reduces Mortality in Patients Aged ≥75 Years with Diffuse Large B-Cell Lymphoma Treated with R-CHOP: A Prospective Cohort Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34990525/
doi: 10.4143/crt.2021.1168. Online ahead of print. 1 Department of Hematology-Oncology, Ajou University Hospital, Suwon, Korea. 2 Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. 3 Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. 4 Department of Internal Medicine, Korea University Anam Hospital, Seoul, Korea.
Conclusion: Pegfilgrastim prophylaxis is effective in the prevention of FN and infection-related death in DLBCL patients receiving R-CHOP, and it also improves OS in patients aged ≥75 years.