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Tumor cells in light-chain amyloidosis and myeloma show different transcriptional rewiring of normal plasma cell development - PubMed

Tumor cells in light-chain amyloidosis and myeloma show different transcriptional rewiring of normal plasma cell development - PubMed

Source :

https://pubmed.ncbi.nlm.nih.gov/34133718/

Although light-chain amyloidosis (AL) and multiple myeloma (MM) are characterized by tumor plasma cell (PC) expansion in bone marrow (BM), their clinical presentation differs. Previous attempts to identify unique pathogenic mechanisms behind such differences were unsuccessful, but there are no studi ...