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Synergistic interaction between HDAC and MCL-1 inhibitors through downregulation of BCL-XL in multiple myeloma - PubMed

Synergistic interaction between HDAC and MCL-1 inhibitors through downregulation of BCL-XL in multiple myeloma - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33910332/

doi: 10.3324/haematol.2020.277152. Online ahead of print. 1 Department of Medicine I, Wilhelminen Cancer Research Institute, Clinic Ottakring, Vienna, Austria; Recipient of a DOC Fellowship of the Austrian Academy of Sciences at the Wilhelminen Cancer Research Institute. 2 Department of Medicine I, Wilhelminen Cancer Research Institute, Clinic Ottakring, Vienna.

  • May 08, 2021
    Will be interesting to see if this bench research on myeloma cell lines can be translated into a clinically useful combination strategy at the bedside