Downregulation of ITGA6 confers to the invasion of multiple myeloma and promotes progression to plasma cell leukaemia - PubMed
Source :
https://pubmed.ncbi.nlm.nih.gov/33785876/doi: 10.1038/s41416-021-01362-5. Online ahead of print. 1 Department of Cell Biology, School of Biology & Basic Medical Sciences, Soochow University, Suzhou, China. 2 Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China. 3 Department of Hematology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
This may be the first study defining the importance of this protein ITGA6 in myeloma. An interesting inverse correlation with disease aggressiveness ...