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A new parameter in multiple myeloma: CYP3A4*1B single nucleotide polymorphism

A new parameter in multiple myeloma: CYP3A4*1B single nucleotide polymorphism

Source : https://link.springer.com/article/10.1007/s00277-020-04339-1

Multiple myeloma (MM) is a disease caused by malignant plasma cells, causing free light chain release accompanying the increase in monoclonal immunoglobulin. Cytochrome P450 (CYP) is one of the large and functional enzyme families composed of various hemoproteins. This protein network has been shown to play a role in many treatment steps in current practices.