Stopping the beating heart of cancer: KRAS reviewed - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34303932/

It has taken four decades of research to see the first major breakthrough for KRAS-driven cancers. In particular, the last decade has seen a paradigm shift with the discovery of druggable pockets on KRAS and clinical efficacy with covalent KRAS G12C inhibitors, culminating in the first app ...