Targeting KRAS in non-small cell lung cancer: recent progress and new approaches - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34089836/

Rat sarcoma (RAS) is the most frequently mutated oncogene in human cancer, with Kirsten rat sarcoma (KRAS) being the most commonly mutated RAS isoform. Overall, KRAS accounts for 85% of RAS mutations observed in human cancers and is present in 35% of lung adenocarcinomas. While the use of targeted t ...