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AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer - PubMed

AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer - PubMed

Source :

https://pubmed.ncbi.nlm.nih.gov/33972443/

Lung cancer is the deadliest malignancy in the United States. Non-small cell lung cancer (NSCLC) accounts for 85% of cases and is frequently driven by activating mutations in the gene encoding the KRAS GTPase (e.g., KRASG12D ). Our previous work demonstrated that Argonaute 2 (AGO2)-a component ...