doi: 10.1186/s13046-021-01938-2. 1 Department of General Thoracic Surgery, Inselspital, Bern University Hospital, Murtenstrasse 50, 3008, Bern, Switzerland. 2 Department of BioMedical Research, University of Bern, Bern, Switzerland. 3 Institute of Pathology, University of Bern, Bern, Switzerland. 4 Thoracic Surgery Department 2, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.