Sensitive Detection of KRAS Mutations by Clustered Regularly Interspaced Short Palindromic Repeats

Source : https://www.mdpi.com/2075-4418/11/1/125/htm

Kirsten rat sarcoma viral oncogene (KRAS) is the isoform most frequently mutated in human tumors. Testing for activating KRAS mutations has important implications for diagnosis and the personalized medicine of cancers. The current techniques for detecting KRAS mutations have moderate sensitivity.