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Immune modulatory effects of oncogenic KRAS in cancer

Immune modulatory effects of oncogenic KRAS in cancer

Source :

https://www.nature.com/articles/s41467-020-19288-6

Oncogenic signalling has been historically associated with sustained cancer cell-intrinsic proliferation, however its role in promoting tumour immunoresistance has also become evident. Here, Hamarsheh and colleagues review and discuss the preclinical work on the immune modulatory effects of oncogenic KRAS and the potential clinical application.