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iCSDB: an integrated database of CRISPR screens

iCSDB: an integrated database of CRISPR screens

Source :

https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa989/5952197

High-throughput screening (HTS) has become an indispensable tool for functional genomics and drug discovery. Genetic loss-of-function (LoF) experiments are frequently used in HTS to identify targets that confer genetic vulnerability in various diseases. RNA interference (RNAi) screening using small-interfering RNA (siRNA) libraries was the method of choice for LoF experiments during the last decade ( 1).