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miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer

miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer

Source :

https://www.nature.com/articles/s41417-020-00224-1

Lung cancer is still the leading cause of death by cancer worldwide despite advances both in its detection and therapy. Multiple oncogenic driver alterations have been discovered, opening the prospective for new potential therapeutic targets.