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Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights

Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights

Source : https://doi.org/10.3389/fimmu.2019.02872

Wnt signaling is one of the central mechanisms regulating tissue morphogenesis during embryogenesis and repair. The pivot of this signaling cascade is the Wnt ligand, which binds to receptors belonging to the Frizzled family or the ROR1/ROR2 and RYK family.

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