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CAIX-specific CAR-T Cells and Sunitinib Show Synergistic... : Journal of Immunotherapy

CAIX-specific CAR-T Cells and Sunitinib Show Synergistic... : Journal of Immunotherapy

Source : https://journals.lww.com/immunotherapy-journal/Abstract/2020/01000/CAIX_specific_CAR_T_Cells_and_Sunitinib_Show.3.aspx

efficacy. Some chemotherapeutic agents exhibit immune microenvironment modulation. Therefore, combination with chemotherapeutic agents may be one of the promising strategies to enhance the therapeutic efficacy of CAR-T against solid tumors. Sunitinib modulates the antitumor immune response by improving T-cell infiltration and function while reducing immunosuppressive factors.

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