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Molecular Design, Optimization, and Genomic Integration of Chimeric B Cell Receptors in Murine B Cells

Molecular Design, Optimization, and Genomic Integration of Chimeric B Cell Receptors in Murine B Cells

Source : https://doi.org/10.3389/fimmu.2019.02630

Immune cell therapies based on the integration of synthetic antigen receptors comprise a powerful strategy for the treatment of diverse diseases, most notably T cells engineered to express chimeric antigen receptors (CAR) for targeted cancer therapy.

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