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The M2 macrophage marker CD206: a novel prognostic indicator for acute myeloid leukemia

The M2 macrophage marker CD206: a novel prognostic indicator for acute myeloid leukemia

Source : https://www.tandfonline.com/doi/full/10.1080/2162402X.2019.1683347

ABSTRACT Hematological malignancies possess a distinctive immunologic microenvironment compared with solid tumors. Here, using an established computational algorithm (CIBERSORT), we systematically analyzed the overall distribution of 22 tumor-infiltrating leukocyte (TIL) populations in more than 2000 bone marrow (BM) samples from 5 major hematological malignancies and healthy controls.

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