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Terminating Cancer by Blocking VISTA as a Novel Immunotherapy: Hasta la vista, baby

Terminating Cancer by Blocking VISTA as a Novel Immunotherapy: Hasta la vista, baby

Source :

https://doi.org/10.3389/fonc.2021.658488

VISTA is an up-and-coming immune checkpoint molecule that can become the target of new cancer immunotherapy treatments. Immune cells in the tumor microenvironment can largely influence the progression of cancer through inhibitory and stimulatory pathways. Indeed, VISTA is expressed on many immune cells, including T cells, myeloid-derived suppressor cells, tumor-associated macrophages, and dendritic cells.