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Identification of FABP5 as an immunometabolic marker in human hepatocellular carcinoma

Identification of FABP5 as an immunometabolic marker in human hepatocellular carcinoma

Source :

https://jitc.bmj.com/content/8/2/e000501

Background Regulating T-cell metabolism is crucial for their anticancer activity. Therefore, understanding the function and metabolism of human tumor-infiltrating T cells is of broad interest and clinical importance. Methods CD3+CD45+ T cells were sorted from adjacent area or tumor core of human hepatocellular carcinoma (HCC), then the clusters and heterogeneity of T cells were further interrogated by single-cell transcriptomic profiling.