Skip to main content
  • Saved

made a Post

Mucosal inflammation predicts response to systemic steroids in immune checkpoint inhibitor colitis

Mucosal inflammation predicts response to systemic steroids in immune checkpoint inhibitor colitis

Source :

https://jitc.bmj.com/content/8/1/e000451

Background Immune-related colitis is a common, often serious complication of immune checkpoint inhibition (ICI). Although endoscopy is not strictly recommended for any grade of diarrhea/colitis, emerging evidence suggests that endoscopic evaluation may have important therapeutic implications. In this retrospective study, we sought to comprehensively characterize the clinical and histologic features of ICI-induced colitis with a specific focus on evaluating the prognostic role of endoscopy.