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Tumors escape immunosurveillance by overexpressing the proteasome activator PSME3

Tumors escape immunosurveillance by overexpressing the proteasome activator PSME3

Source :

https://doi.org/10.1080/2162402X.2020.1761205

ABSTRACT The success of CD8+ T cell-based cancer immunotherapy emphasizes the importance of understanding the mechanisms of generation of MHC-I peptide ligands and the possible pathways of tumor cell escape from immunosurveillance.