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Staphylococcus aureus alpha-toxin inhibits CD8  T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma

Staphylococcus aureus alpha-toxin inhibits CD8 T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma

Source :

https://doi.org/10.1080/2162402X.2020.1751561

ABSTRACT ABSTRACT Staphylococcus aureus and its toxins have been linked to disease progression and mortality in advanced stages of cutaneous T-cell lymphoma (CTCL). CD8 T cells play a crucial role in anti-cancer responses and high CD8 T cell numbers in tumor lesions are associated with a favorable prognosis in CTCL.